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Nodes and edges are weighted according to the number of studies including the respective interventions.Fig 1 Network plot of treatment comparisons. Similarly, when compared with LMWH plus GpIIb/IIIa inhibitor, unfractionated heparin was associated with a higher risk of major adverse cardiovascular event (relative risk 2.56 (1.30 to 5.00)), as were bivalirudin (relative risk 2.27 (1.15 to 4.54)) and fondaparinux (relative risk 3.03 (1.30 to 7.14)) (fig 2). In the probability analysis the hierarchy for treatment efficacy for major adverse cardiovascular event (highest to lowest rank) was LMWH plus GpIIb/IIIa inhibitor, followed by unfractionated heparin plus GpIIb/IIIa inhibitor, bivalirudin, unfractionated heparin, and fondaparinux (supplementary fig 2).

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